WillSpirit!

Where Will meets Spirit
∞ Love, Clarity, Balance, Peace, & Bliss ∞

A science, mental health and spirituality blog written by a physician.








  • Red_Exclamation_DotDisclaimer
    • Dear Visitors:
      Although I trained and practiced as a physician, my background does not include formal instruction in psychiatry beyond basic medical education. This journal presents ideas about treatment philosophy, but must not be considered therapeutic advice. Abrupt changes in one's psychiatric medications can trigger profound cognitive, emotional, and physical symptoms, including suicidal thoughts and actions. Consequently, pharmaceutical agents should not be increased or decreased without supervision by a mental health clinician.

    • ON THE OTHER HAND, your brain belongs to you, and your opinion counts. If you decide that changing your medication regimen will serve your best interest, then I believe your providers have an obligation to help you try to achieve your goals. I want everyone to be educated about their options, and do what will be most helpful for themselves. No one should feel pushed around by dogmatic and/or limited viewpoints, whether those of psychiatrists, anti-psychiatry advocates, or myself.


A Dance of DNA, History, and Soul


The following post is my next installment in a writing project that began on 20 October. Although it stands on its own as an essay, you can view it in context if you work forward from the first entry in the series.

The next step in this series is to start talking about my upbringing and why it led to problems with mood instability. This shifts the focus from viewing the general picture to looking at a particular case. And yet, what follows is not just my story, but every story. The details differ, but we all have suffered good and bad times, we’ve all been hurt, and we’ve all learned from experience. We’ve also all developed in a womb and we face the same end. In truth, the differences are far less impressive than the similarities. Keep that in mind while reading my unique personal history, and pay attention to how my particular trajectory reflects the human condition as we all live it.

At the outset of this writing project I said this story would start at the beginning. So let’s go right back to my first moment: that of conception. I don’t mean to raise the abortion debate here, so understand that my point isn’t necessarily that my soul manifested at the exact instant a minuscule, writhing spermatozoon from my dad penetrated the massive, nutrient packed ovum produced by my mom. But until then, the universe had never before seen that precise combination of genetic and epigenetic information gathered in a single cell. At that moment, a goodly portion of my fate was sealed.

The moodiness so common in my mother’s family (as well as her artistic sensibilities) and the alcoholism so common among my father’s relations (as well is his analytical prowess) were carried forward to me in that mix of DNA. But just how moody, artistic, alcoholic, or analytical I became remained to be shaped by time and circumstance.

As the fertilized egg divided, then divided again, as it grew into a solid ball of cells in those first few hours and days, it was affected by the chemical mix of my mother’s fluids. Her hormones and cellular messages affected my rapidly expanding mass of protoplasm. By the time I implanted in her uterine wall and the love affair of blood vessels known as a placenta formed, I’d already tapped many sources of information not present at conception. As I developed in her uterus, my little growing body continued to be affected by myriad substances, sounds, and motions. Her breathing and heart rate formed the universe of my mood at that time. If she felt worried and depressed, I shivered in my dark, watery world. If she laughed with ecstatic delight, I shimmied with pleasure.

And if she took a medication, which was commonly done by pregnant women in those days, I took it too. If pesticides entered her bloodstream, they entered mine. When she smoked or drank, I felt the rush of nicotine or the loosening of alcohol. If she walked near the exhaust of an automobile, the fumes from leaded gasoline entered her lungs and moments later a heavy metal circulated through my nervous system as it produced millions of vulnerable growing cells each hour.

At the same time, the thousands of genes on my DNA molecules were orchestrating my formation. My sex, coloration, facial features, and internal arrangements were laid down. I took the form of a European male baby because I carried European genes and a Y chromosome. It is likely that brain structures were genetically shaped in ways that determined many personality traits: my introversion, my sensitivity, maybe even my seriousness.

And yet all these genetic traits were modified at every moment by countless influences from outside. The genes were painting my portrait using pigments acquired from the environment.

Did a separate soul enter at some point? Did a consciousness already familiar with birth and death take residence in that little baby growing inside a moody woman in 1958? Do we play this game of life over and over as reincarnationists believe? It isn’t possible to be sure. I’ve read the evidence that supports the concept and find it intriguing but not quite decisive. The jury is out. But there is little doubt that the person who I became differs in important ways from everyone else in my family, even as we also share many traits. Whence the source of that uniqueness? Genes? Environment? Prior lives? The touch of God?

All I know for sure is that the day came when my mother’s womb decided my time had come, and uterine contractions pushed me into the waiting world. For better or worse, my qualities were already guiding me down my own unique path. Even at that early stage I was already the product of both my genes and the emotional and chemical milieu which formed me, which nurtured me as I grew from a single cell into a lively baby in just nine months.

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Am I too Smart to be Happy?

Ernest Hemingway once said that intelligent people are rarely happy.

Having always been more of a Faulkner than a Hemingway fan, I’m going to disagree with Ernest. I know many intelligent, happy people. Of course, often they are Buddhist meditators, or in AA, or involved in some other framework that helps them address the challenges of life. It takes work to be happy, and intelligent people may need to work harder because they can see more problems than those with simpler outlooks. But intelligence is not a major obstacle to happiness, in my opinion.

It is well-recognized that many creative people have mood issues. Poets suffer notoriously high suicide rates, and Hemingway obviously falls into this category of moody artist. In many cases, the artist uses his or her medium to give voice to emotional turmoil. The biographies of mentally distressed artists and authors often reveal upbringings light on love, or heavy on cruelty and loss, or both. I suspect that artistry and moodiness spring from the same sources, and doubt that creativity by itself causes depression and other affective difficulties. (Some authorities, including Kay Redfield Jamison, might disagree.) The movie Amadeus comes to mind; it depicts Mozart’s genius and instability in counterpoint to his father’s domineering and critical attitude.

Childhood hardship, especially if severe, radically diminishes the chances for spontaneous adult happiness. Modern research suggests that emotionally or physically threatening experiences alter the brain’s fine structure, and these changes linger. Because my stepmother often crept into my childhood bedroom to wake me up and vent her anger, sometimes by strangulation, I occasionally jump up screaming in the dead of night. This happens less and less often as I work through my emotional wounds, but whatever she did to my nervous system has persisted into my fifties. The brain remembers, even if consciousness doesn’t (in my case I believe my recollections of childhood trauma are pretty complete, but many people have blank spaces in memory that keep traumatic histories more or less beneath awareness.)

We hear a lot of talk about the biological underpinnings of mental illness. In my family there are stark examples where people of roughly the same genetic stock have very different levels of mental well being. Without exception, the ones who have the biggest personality and emotional problems are those who suffered trauma in childhood. My relatives who were fortunate to have been raised in loving, stable environments have escaped mood and personality disorders. This dovetails with what I’ve observed in my professional and volunteer work among the mentally ill, and with much (thought not all) of what I’ve read in technical literature.

Biology establishes a predisposition, but major mental illness is most likely to occur when people with genetic tendencies also suffer childhood mistreatment. This is definitely true in mood and personality disorders; schizophrenia might be different, though even here some people believe trauma plays a decisive role. Without mistreatment, there may be moodiness or quirkiness, but it does not as frequently become crippling.

Childhood trauma makes joy in life difficult, but not impossible. Sensitive, intelligent people feel and see more of the pain in the world. This makes it more challenging to remain upbeat, but unhappiness is not fated. Painful upbringings, intelligence, creativity, and genetic predisposition all play roles in mood disorders. I’m arguing that the first is by far the largest contributor to unhappiness, but no combination of circumstances is absolutely insurmountable.

Still, happiness takes work. It demands attention to thought and behavior, and is promoted by searching for meaning in life. Meditation, exercise, study, and social activities all contribute. Many people make progress with therapy and/or medication.

Always remember that neither the past, nor one’s abilities, nor one’s genes, completely determine the future. As someone who long despaired of ever feeling good about life, I can now attest that even dreadful childhood trauma and loss (plus whatever measure of intelligence and creativity I possess) do not necessarily prevent happiness. There is hope. Always, there is hope.

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